

| Número de catálogo | HB135014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-CD155/PVR Polyclonal Antibody (HB135014) is a rabbit polyclonal antibody detecting CD155 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human CD155/PVR (Trp21-Asn343). | ||||||||
| Objetivo | Nectin-like protein 5, Poliovirus receptor, CD155, PVR, PVS, NECL-5 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P15151 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Poliovirus receptor (CD155/PVR) is a ~45 kDa protein. Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytotoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. | ||||||||
| Nota | For research use only. |

Western blot analysis was performed using anti-PVR polyclonal antibody at 1μg/ml on various samples.
Lane 1: Hela cell lysate
Lane 2: A549 cell lysate
Lane 3: HUVEC cell lysate
Lane 4: LO2 cell lysate




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