

| Numéro de catalogue | HF719014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-CD218b/IL18RAP Polyclonal Antibody (HF719014) is a rabbit polyclonal antibody detecting IL18RAP in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human CD218b/IL18RAP (Phe20-Arg356). | ||||||||
| Cible | AcPL, Accessory protein-like, Interleukin-1 receptor 7, IL-18R-beta, CD218 antigen-like family member B, IL-1RAcPL, Interleukin-18 receptor accessory protein, CDw218b, IL-1R-7, IL1R7, IL-1R7, IL-18RAcP, CD218b, IL-1R accessory protein-like, IL18RAP, Interleukin-18 receptor accessory protein-like, IL-18 receptor accessory protein, IL-18Rbeta, Interleukin-18 receptor beta | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O95256 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Interleukin-18 receptor accessory protein (CD218b/IL18RAP) is a ~68 kDa protein. Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable). 1. Kato, Z. et al. (2003) Nature structural biology 10, 966-71. PMID: 14528293 2. Tsutsumi, N. et al. (2014) Nature communications 5, 5340. PMID: 25500532 3. Born, TL. et al. (1998) The Journal of biological chemistry 273, 29445-50. PMID: 9792649 | ||||||||
| Note | For research use only. |




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