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| カタログ番号 | HF719014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-CD218b/IL18RAP Polyclonal Antibody (HF719014) is a rabbit polyclonal antibody detecting IL18RAP in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CD218b/IL18RAP (Phe20-Arg356). | ||||||||
| ターゲット | AcPL, Accessory protein-like, Interleukin-1 receptor 7, IL-18R-beta, CD218 antigen-like family member B, IL-1RAcPL, Interleukin-18 receptor accessory protein, CDw218b, IL-1R-7, IL1R7, IL-1R7, IL-18RAcP, CD218b, IL-1R accessory protein-like, IL18RAP, Interleukin-18 receptor accessory protein-like, IL-18 receptor accessory protein, IL-18Rbeta, Interleukin-18 receptor beta | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O95256 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Interleukin-18 receptor accessory protein (CD218b/IL18RAP) is a ~68 kDa protein. Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable). 1. Kato, Z. et al. (2003) Nature structural biology 10, 966-71. PMID: 14528293 2. Tsutsumi, N. et al. (2014) Nature communications 5, 5340. PMID: 25500532 3. Born, TL. et al. (1998) The Journal of biological chemistry 273, 29445-50. PMID: 9792649 | ||||||||
| 注意事項 | For research use only. |
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