Anti-Human CD23 Polyclonal Antibody (HY541014)

Name: Anti-Human CD23 Polyclonal Antibody
Brand: abinScience
SKU: HY541014
Price: 168 USD
Availability: InStock

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50ug
100ug

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Aperçu

Numéro de catalogue

HY541014

Description

Anti-CD23/FCER2 Polyclonal Antibody (HY541014) is a rabbit polyclonal antibody detecting FCER2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human CD23/FCER2 (Asp48-Ser321).

Cible

Lymphocyte IgE receptor, C-type lectin domain family 4 member J, Low affinity immunoglobulin epsilon Fc receptor, CD23A, BLAST-2, Immunoglobulin E-binding factor, IGEBF, CD23, Fc-epsilon-RII, CLEC4J, FCE2, FCER2

Purification

Purified by antigen affinity column.

Numéro d'accès

P06734

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Low affinity immunoglobulin epsilon Fc receptor (CD23/FCER2) is a ~36 kDa protein. Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway.

1. Pirron, U. et al. (1990) European journal of immunology 20, 1547-51. PMID: 2167225

2. Vouldoukis, I. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 7804-8. PMID: 7544003

Note

For research use only.

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