

| Numéro de catalogue | HF626014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human Band 3 Polyclonal Antibody (HF626014) is a rabbit polyclonal antibody detecting Band 3 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant CD233/SLC4A1 (Ala35-Ser290). | ||||||||
| Cible | AE 1, AE1, Anion exchange protein 1, Anion exchanger 1, Band 3 anion transport protein, CD233, DI, EPB3, SLC4A1, Solute carrier family 4 member 1 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Pureté | >95% as determined by SDS-PAGE. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P02730 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||||
| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Band 3 anion transport protein (CD233/SLC4A1) is a ~101 kDa protein. Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Component of the ankyrin-1 complex of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine. 1. Bruce, LJ. et al. (2000) The Biochemical journal 350 Pt 1, 41-51. PMID: 10926824 2. Rungroj, N. et al. (2004) The Journal of biological chemistry 279, 13833-8. PMID: 14734552 3. Schofield, AE. et al. (1992) Journal of molecular biology 223, 949-58. PMID: 1538405 4. Bruce, LJ. et al. (2005) Nature genetics 37, 1258-63. PMID: 16227998 5. Ungsupravate, D. et al. (2010) Molecular membrane biology 27, 92-103. PMID: 20151848 6. Shnitsar, V. et al. (2013) The Journal of biological chemistry 288, 33848-33860. PMID: 24121512 7. Genetet, S. et al. (2017) Scientific reports 7, 46170. PMID: 28387307 8. Vallese, F. et al. (2022) Nature structural & molecular biology 29, 706-718. PMID: 35835865 | ||||||||
| Note | For research use only. |




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