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Anti-CD244 Polyclonal Antibody (HV513014)

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Vista general
Número de catálogoHV513014
Descripción
Anti-CD244 Polyclonal Antibody (HV513014) is a rabbit polyclonal antibody detecting CD244 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human CD244 (Cys22-Pro229).
Objetivo SLAM family member 4, SLAMF4, h2B4, Signaling lymphocytic activation molecule 4, Natural killer cell receptor 2B4, NKR2B4, NAIL, NK cell type I receptor protein 2B4, CD244, NK cell activation-inducing ligand, 2B4
Purificación Purified by antigen affinity column.
Número de acceso Q9BZW8
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Natural killer cell receptor 2B4 (CD244) is a ~41 kDa protein. Heterophilic receptor of the signaling lymphocytic activation molecule (SLAM) family; its ligand is CD48. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Acts as activating natural killer (NK) cell receptor. Activating function implicates association with SH2D1A and FYN.

1. Nakajima, H. et al. (1999) European journal of immunology 29, 1676-83. PMID: 10359122
2. Speiser, DE. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 6165-70. PMID: 11714776
3. Valiante, NM. et al. (1993) The Journal of experimental medicine 178, 1397-406. PMID: 8376943
4. Eissmann, P. et al. (2005) Blood 105, 4722-9. PMID: 15713798
5. Parolini, S. et al. (2000) The Journal of experimental medicine 192, 337-46. PMID: 10934222
6. Sivori, S. et al. (2000) European journal of immunology 30, 787-93. PMID: 10741393
7. Sivori, S. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 4526-31. PMID: 11917118
Nota For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-CD244 Polyclonal Antibody

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