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Обзор
Каталожный номерHV513014
Описание
Anti-CD244 Polyclonal Antibody (HV513014) is a rabbit polyclonal antibody detecting CD244 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Реактивность видовHuman
ПримененияELISA, IHC, WB
Хозяинский видRabbit
КлоональностьPolyclonal
ИзотипIgG
Иммуноген E. coli - derived recombinant Human CD244 (Cys22-Pro229).
Цель SLAM family member 4, SLAMF4, h2B4, Signaling lymphocytic activation molecule 4, Natural killer cell receptor 2B4, NKR2B4, NAIL, NK cell type I receptor protein 2B4, CD244, NK cell activation-inducing ligand, 2B4
Очистка Purified by antigen affinity column.
Номер доступа Q9BZW8
Форма Liquid
Буфер хранения 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта
Применение Разбавление
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

Natural killer cell receptor 2B4 (CD244) is a ~41 kDa protein. Heterophilic receptor of the signaling lymphocytic activation molecule (SLAM) family; its ligand is CD48. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Acts as activating natural killer (NK) cell receptor. Activating function implicates association with SH2D1A and FYN.

1. Nakajima, H. et al. (1999) European journal of immunology 29, 1676-83. PMID: 10359122
2. Speiser, DE. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 6165-70. PMID: 11714776
3. Valiante, NM. et al. (1993) The Journal of experimental medicine 178, 1397-406. PMID: 8376943
4. Eissmann, P. et al. (2005) Blood 105, 4722-9. PMID: 15713798
5. Parolini, S. et al. (2000) The Journal of experimental medicine 192, 337-46. PMID: 10934222
6. Sivori, S. et al. (2000) European journal of immunology 30, 787-93. PMID: 10741393
7. Sivori, S. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 4526-31. PMID: 11917118
Примечание For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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