

| Каталожный номер | HS759014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-CD281/TLR1 Polyclonal Antibody (HS759014) is a rabbit polyclonal antibody detecting CD281 in ELISA, IHC, WB. Suitable for Human and Bovine.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human CD281/TLR1 (Asn625-Lys786). | ||||||||
| Цель | Toll/interleukin-1 receptor-like protein, CD281, Toll-like receptor 1, TIL, KIAA0012, TLR1 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q15399 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Toll-like receptor 1 (CD281/TLR1) is a ~90 kDa protein. Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Forms the activation cluster TLR2:TLR1:CD14 in response to triacylated lipopeptides, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. 1. Lancioni, CL. et al. (2011) Infection and immunity 79, 663-73. PMID: 21078852 2. Triantafilou, M. et al. (2006) The Journal of biological chemistry 281, 31002-11. PMID: 16880211 | ||||||||
| Примечание | For research use only. |



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