

| Numéro de catalogue | HW505014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-CD292/BMPR1A Polyclonal Antibody (HW505014) is a rabbit polyclonal antibody detecting BMPR1A in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human CD292/BMPR1A (Gln24-Arg152). | ||||||||
| Cible | ACVRLK3, Bone morphogenetic protein receptor type-1A, ALK3, BMPR-1A, Serine/threonine-protein kinase receptor R5, SKR5, Activin receptor-like kinase 3, ALK-3, BMP type-1A receptor, BMPR1A, CD292 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P36894 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Bone morphogenetic protein receptor type-1A (CD292/BMPR1A) is a ~60 kDa protein. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6. | ||||||||
| Note | For research use only. |




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