Anti-Human TIM-3 Polyclonal Antibody (HV029014)

Name: Anti-Human TIM-3 Polyclonal Antibody
Brand: abinScience
SKU: HV029014
Price: 168 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD):

Especificación:

50ug
100ug

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HV029014

Descripción

Anti-CD366/HAVCR2/TIM-3 Polyclonal Antibody (HV029014) is a rabbit polyclonal antibody detecting HAVCR2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human CD366/HAVCR2/TIM-3 (Ser22-Arg200).

Objetivo

CD366, HAVCR2, HAVcr-2, Hepatitis A virus cellular receptor 2, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIM-3, TIM3, TIMD-3, TIMD3

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>90% as determined by SDS-PAGE.

Purificación

Purified by antigen affinity column.

Número de acceso

Q8TDQ0

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Hepatitis A virus cellular receptor 2 (CD366/TIM-3) is a ~33 kDa protein. Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand. Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance.

1. Gorman, JV. et al. (2014) Immunologic research 59, 56-65. PMID: 24825777

2. Monney, L. et al. (2002) Nature 415, 536-41. PMID: 11823861

3. Sánchez-Fueyo, A. et al. (2003) Nature immunology 4, 1093-101. PMID: 14556005

4. Clayton, KL. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 192, 782-91. PMID: 24337741

5. Tomkowicz, B. et al. (2015) PloS one 10, e0140694. PMID: 26492563

6. Gautron, AS. et al. (2014) European journal of immunology 44, 2703-2711. PMID: 24838857

7. Zhu, C. et al. (2005) Nature immunology 6, 1245-52. PMID: 16286920

8. Leitner, J. et al. (2013) PLoS pathogens 9, e1003253. PMID: 23555261

9. Gleason, MK. et al. (2012) Blood 119, 3064-72. PMID: 22323453

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human TIM-3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo