Anti-Human Integrin beta 3/CD61 Polyclonal Antibody (HY323014)

Name: Anti-Human Integrin beta 3/CD61 Polyclonal Antibody
Brand: abinScience
SKU: HY323014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
100ug

Número:

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Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HY323014

Descripción

Anti-CD61/ITGB3 Polyclonal Antibody (HY323014) is a rabbit polyclonal antibody detecting ITGB3 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human CD61/ITGB3 (Glu134-Glu384).

Objetivo

GPIIIa, Integrin beta-3, CD61, ITGB3, Platelet membrane glycoprotein IIIa, GP3A

Purificación

Purified by antigen affinity column.

Número de acceso

P05106

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Integrin beta-3 (CD61/ITGB3) is a ~87 kDa protein. Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 (ITGA2B:ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen.

1. Si-Tahar, M. et al. (1997) The Journal of biological chemistry 272, 11636-47. PMID: 9111081

2. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415

3. Fujita, M. et al. (2014) PloS one 9, e96372. PMID: 24789099

4. Ieguchi, K. et al. (2010) The Journal of biological chemistry 285, 31388-98. PMID: 20682778

5. Mori, S. et al. (2008) The Journal of biological chemistry 283, 18066-75. PMID: 18441324

6. Mori, S. et al. (2017) Bioscience reports 37. PMID: 28302677

7. Saegusa, J. et al. (2009) The Journal of biological chemistry 284, 24106-14. PMID: 19578119

8. Cedano Prieto, DM. et al. (2017) PloS one 12, e0184285. PMID: 28873464

9. Takada, YK. et al. (2017) The Journal of biological chemistry 292, 20067-20075. PMID: 29030430

10. Saegusa, J. et al. (2008) The Journal of biological chemistry 283, 26107-15. PMID: 18635536

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human Integrin beta 3/CD61 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

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