Anti-Human CEACAM-5/CD66e Polyclonal Antibody (HY546014)

Name: Anti-Human CEACAM-5/CD66e Polyclonal Antibody
Brand: abinScience
SKU: HY546014
Price: 96 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HY546014

説明

Anti-CD66e/CEA/CEACAM5 Polyclonal Antibody (HY546014) is a rabbit polyclonal antibody detecting CEACAM5 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

種反応性

Human

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human CD66e/CEA/CEACAM5 (Ala34-Leu234).

テスト済みアプリケーション

ターゲット

CD66e, CEA, CEA cell adhesion molecule 5, CEACAM5, Carcinoembryonic antigen, Carcinoembryonic antigen-related cell adhesion molecule 5, Cell adhesion molecule CEACAM5, Meconium antigen 100

エンドトキシンレベル

Please contact with the lab for this information.

純度

>90% as determined by SDS-PAGE.

精製

Purified by antigen affinity column.

アクセッション番号

P06731

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Cell adhesion molecule CEACAM5 (CD66e) is a ~76 kDa protein. Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells.

1. Taheri, M. et al. (2000) The Journal of biological chemistry 275, 26935-43. PMID: 10864933

2. Ordoñez, C. et al. (2000) Cancer research 60, 3419-24. PMID: 10910050

3. Oikawa, S. et al. (1989) Biochemical and biophysical research communications 164, 39-45. PMID: 2803308

注意事項

For research use only.

イメージ

Western blot

Western blot analysis was performed using anti-CEACAM5 polyclonal antibody at 1ug/mL on various samples.
Lane 1: HT-29 cell lysate
Lane 2: MCF-7 cell lysate
Lane 3: BxPC-3 cell lysate
Lane 4: SW620 cell lysate