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Anti-Human CD84/SLAMF5 Polyclonal Antibody (HV297014)

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Vista general
Número de catálogoHV297014
Descripción
Anti-CD84 Polyclonal Antibody (HV297014) is a rabbit polyclonal antibody detecting CD84 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human CD84 (Ile43-Leu248).
Objetivo Signaling lymphocytic activation molecule 5, Hly9-beta, Cell surface antigen MAX.3, Leukocyte differentiation antigen CD84, CD84, SLAM family member 5, SLAMF5
Purificación Purified by antigen affinity column.
Número de acceso Q9UIB8
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

SLAM family member 5 (CD84) is a ~38 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Can mediate natural killer (NK) cell cytotoxicity dependent on SH2D1A and SH2D1B. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seem be required for this process.

1. Martin, M. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 3668-76. PMID: 11564780
2. Tangye, SG. et al. (2002) European journal of immunology 32, 1640-9. PMID: 12115647
3. Tangye, SG. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 171, 2485-95. PMID: 12928397
4. Zaiss, M. et al. (2003) Experimental hematology 31, 798-805. PMID: 12962726
5. Nanda, N. et al. (2005) Blood 106, 3028-34. PMID: 16037392
6. Álvarez-Errico, D. et al. (2011) Journal of immunology (Baltimore, Md. : 1950) 187, 5577-86. PMID: 22068234
7. Agod, Z. et al. (2018) Frontiers in immunology 9, 62. PMID: 29434592
Nota For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human CD84/SLAMF5 Polyclonal Antibody

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