

| Número de catálogo | HY433014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-CD8B Polyclonal Antibody (HY433014) is a rabbit polyclonal antibody detecting CD8B in ELISA, IHC, WB. Suitable for Human and Pongo pygmaeus.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human CD8B (Leu22-Pro170). | ||||||||
| Objetivo | CD8B1, T-cell surface glycoprotein CD8 beta chain, CD8B, CD8b | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P10966 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | T-cell surface glycoprotein CD8 beta chain (CD8B) is a ~23 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. | ||||||||
| Nota | For research use only. |
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