

| Numéro de catalogue | HY433014 | ||||||||
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| Description |
Anti-CD8B Polyclonal Antibody (HY433014) is a rabbit polyclonal antibody detecting CD8B in ELISA, IHC, WB. Suitable for Human and Pongo pygmaeus.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human CD8B (Leu22-Pro170). | ||||||||
| Cible | CD8B1, T-cell surface glycoprotein CD8 beta chain, CD8B, CD8b | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P10966 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | T-cell surface glycoprotein CD8 beta chain (CD8B) is a ~23 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. | ||||||||
| Note | For research use only. |
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