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| カタログ番号 | HB873014 | ||||||||
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| 説明 |
Anti-CD95/FAS Polyclonal Antibody (HB873014) is a rabbit polyclonal antibody detecting CD95 in ELISA, IHC, WB. Suitable for Human, Cercocebus atys, Macaca fascicularis, Macaca mulatta, and Macaca nemestrina.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CD95/FAS (Gln26-Asn173). | ||||||||
| ターゲット | APT1, TNFRSF6, FAS1, FASLG receptor, CD95, Apo-1 antigen, Tumor necrosis factor receptor superfamily member 6, FAS, Apoptosis-mediating surface antigen FAS | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P25445 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Tumor necrosis factor receptor superfamily member 6 (CD95/FAS) is a ~37 kDa protein. Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). | ||||||||
| 注意事項 | For research use only. |
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