中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HY415014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-CD98/SLC3A2 Polyclonal Antibody (HY415014) is a rabbit polyclonal antibody detecting SLC3A2 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
||||||||
| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CD98/SLC3A2 (Leu213-Asp349). | ||||||||
| ターゲット | SLC3A2, 4F2hc, Lymphocyte activation antigen 4F2 large subunit, CD98, 4F2 cell-surface antigen heavy chain, Solute carrier family 3 member 2, MDU1, 4F2 heavy chain antigen | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 純度 | >95% as determined by SDS-PAGE. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P08195 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Amino acid transporter heavy chain SLC3A2 (CD98) is a ~57 kDa protein. Acts as a chaperone that facilitates biogenesis and trafficking of functional transporters heterodimers to the plasma membrane. Forms heterodimer with SLC7 family transporters (SLC7A5, SLC7A6, SLC7A7, SLC7A8, SLC7A10 and SLC7A11), a group of amino-acid antiporters. Heterodimers function as amino acids exchangers, the specificity of the substrate depending on the SLC7A subunit. Heterodimers SLC3A2/SLC7A6 or SLC3A2/SLC7A7 mediate the uptake of dibasic amino acids. Heterodimer SLC3A2/SLC7A11 functions as an antiporter by mediating the exchange of extracellular anionic L-cystine and intracellular L-glutamate across the cellular plasma membrane. 1. Rossier, G. et al. (1999) The Journal of biological chemistry 274, 34948-54. PMID: 10574970 2. Bröer, A. et al. (2000) The Biochemical journal 349 Pt 3, 787-95. PMID: 10903140 3. Yanagida, O. et al. (2001) Biochimica et biophysica acta 1514, 291-302. PMID: 11557028 4. Yan, R. et al. (2019) Nature 568, 127-130. PMID: 30867591 5. Yan, R. et al. (2020) Cell discovery 6, 82. PMID: 33298890 6. Yan, R. et al. (2021) Cell discovery 7, 16. PMID: 33758168 7. Parker, JL. et al. (2021) Nature communications 12, 7147. PMID: 34880232 8. Mastroberardino, L. et al. (1998) Nature 395, 288-91. PMID: 9751058 9. Torrents, D. et al. (1998) The Journal of biological chemistry 273, 32437-45. PMID: 9829974 10. Pfeiffer, R. et al. (1999) The EMBO journal 18, 49-57. PMID: 9878049 | ||||||||
| 注意事項 | For research use only. |
お問い合わせ
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
