Anti-CDC42 Polyclonal Antibody (HX069014)

Name: Anti-CDC42 Polyclonal Antibody
Brand: abinScience
SKU: HX069014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HX069014

説明

Anti-CDC42 Polyclonal Antibody (HX069014) is a rabbit polyclonal antibody detecting CDC42 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Aedes aegypti.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse, Rat

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human CDC42 (Met1-Cys188).

ターゲット

CDC42, G25K GTP-binding protein, Cell division control protein 42 homolog

精製

Purified by antigen affinity column.

アクセッション番号

P60953

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Cell division control protein 42 homolog (CDC42) is a ~21 kDa protein. Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration.

1. Oceguera-Yanez, F. et al. (2005) The Journal of cell biology 168, 221-32. PMID: 15642749

2. Modzelewska, K. et al. (2006) The Journal of biological chemistry 281, 37527-35. PMID: 17038317

3. Hong, IK. et al. (2012) The Journal of biological chemistry 287, 32027-39. PMID: 22843693

4. Gauthier-Campbell, C. et al. (2004) Molecular biology of the cell 15, 2205-17. PMID: 14978216

5. Majmundar, AJ. et al. (2021) Science advances 7. PMID: 33523862

6. Schlam, D. et al. (2015) Nature communications 6, 8623. PMID: 26465210

7. Ninomiya, K. et al. (2021) Journal of cell science 134. PMID: 33310911

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-CDC42 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-CDC42 Polyclonal Antibody (HX069014)

概要

イメージ

参考文献

データシート

SDS