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| カタログ番号 | HB451014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-CDK2AP2 Polyclonal Antibody (HB451014) is a rabbit polyclonal antibody detecting Cyclin-dependent kinase 2-associated protein 2; CDK2-associated protein 2; DOC-1-related protein; DOC-1R; CDK2AP2; DOC1R in ELISA, IHC, WB. Suitable for Human, Bovine, and Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human CDK2AP2 (Asn49-Thr126). | ||||||||
| ターゲット | Cyclin-dependent kinase 2-associated protein 2; CDK2-associated protein 2; DOC-1-related protein; DOC-1R; CDK2AP2; DOC1R | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O75956, Q58CN7, Q9CPY4 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Cyclin-dependent kinase 2-associated protein 2 (CDK2AP2) is a ~13 kDa protein. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation; represses CDK2 activation by inhibiting its interaction with cyclin E and A. Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes. 1. Spruijt, CG. et al. (2021) The FEBS journal 288, 3231-3245. PMID: 33283408 2. Liu, Q. et al. (2013) International journal of biological sciences 9, 541-9. PMID: 23781148 | ||||||||
| 注意事項 | For research use only |
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