

| Каталожный номер | HB451014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-CDK2AP2 Polyclonal Antibody (HB451014) is a rabbit polyclonal antibody detecting Cyclin-dependent kinase 2-associated protein 2; CDK2-associated protein 2; DOC-1-related protein; DOC-1R; CDK2AP2; DOC1R in ELISA, IHC, WB. Suitable for Human, Bovine, and Mouse.
Highlights
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| Реактивность видов | Human, Mouse | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant human CDK2AP2 (Asn49-Thr126). | ||||||||
| Цель | Cyclin-dependent kinase 2-associated protein 2; CDK2-associated protein 2; DOC-1-related protein; DOC-1R; CDK2AP2; DOC1R | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | O75956, Q58CN7, Q9CPY4 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Cyclin-dependent kinase 2-associated protein 2 (CDK2AP2) is a ~13 kDa protein. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation; represses CDK2 activation by inhibiting its interaction with cyclin E and A. Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes. 1. Spruijt, CG. et al. (2021) The FEBS journal 288, 3231-3245. PMID: 33283408 2. Liu, Q. et al. (2013) International journal of biological sciences 9, 541-9. PMID: 23781148 | ||||||||
| Примечание | For research use only |
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