

| Número de catálogo | HW830014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-CDKN1B Polyclonal Antibody (HW830014) is a rabbit polyclonal antibody detecting CDKN1B in ELISA, IHC, WB. Suitable for Dog, Cricetulus griseus, Cat, Human, and Mouse.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human CDKN1B (Met1-Thr198). | ||||||||
| Objetivo | Cyclin-dependent kinase inhibitor 1B, KIP1, CDKN1B, p27Kip1, Cyclin-dependent kinase inhibitor p27 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P46527 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Cyclin-dependent kinase inhibitor 1B (CDKN1B) is a ~22 kDa protein. Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. 1. McGrath, DA. et al. (2017) The EMBO journal 36, 2251-2262. PMID: 28666995 | ||||||||
| Nota | For research use only. |
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