Anti-CDKN1B Polyclonal Antibody (HW830014)

Name: Anti-CDKN1B Polyclonal Antibody
Brand: abinScience
SKU: HW830014
Price: 168 USD
Availability: InStock

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HW830014

Description

Anti-CDKN1B Polyclonal Antibody (HW830014) is a rabbit polyclonal antibody detecting CDKN1B in ELISA, IHC, WB. Suitable for Dog, Cricetulus griseus, Cat, Human, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human CDKN1B (Met1-Thr198).

Cible

Cyclin-dependent kinase inhibitor 1B, KIP1, CDKN1B, p27Kip1, Cyclin-dependent kinase inhibitor p27

Purification

Purified by antigen affinity column.

Numéro d'accès

P46527

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Cyclin-dependent kinase inhibitor 1B (CDKN1B) is a ~22 kDa protein. Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation.

1. McGrath, DA. et al. (2017) The EMBO journal 36, 2251-2262. PMID: 28666995

Note

For research use only.

Images

Reférences

Fiche technique

Anti-CDKN1B Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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