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| カタログ番号 | HW830014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-CDKN1B Polyclonal Antibody (HW830014) is a rabbit polyclonal antibody detecting CDKN1B in ELISA, IHC, WB. Suitable for Dog, Cricetulus griseus, Cat, Human, and Mouse.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CDKN1B (Met1-Thr198). | ||||||||
| ターゲット | Cyclin-dependent kinase inhibitor 1B, KIP1, CDKN1B, p27Kip1, Cyclin-dependent kinase inhibitor p27 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P46527 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Cyclin-dependent kinase inhibitor 1B (CDKN1B) is a ~22 kDa protein. Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. 1. McGrath, DA. et al. (2017) The EMBO journal 36, 2251-2262. PMID: 28666995 | ||||||||
| 注意事項 | For research use only. |
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