Anti-CEBPA Polyclonal Antibody (HW834024)

Name: Anti-CEBPA Polyclonal Antibody
Brand: abinScience
SKU: HW834024
Price: 168 USD
Availability: InStock

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50ug
100ug

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Datasheet
SDS

Vista general

Número de catálogo

HW834024

Descripción

Anti-CEBPA Polyclonal Antibody (HW834024) is a rabbit polyclonal antibody detecting CCAAT/enhancer-binding protein alpha; C/EBP alpha; CEBPA; CEBP in ELISA, IHC, WB. Suitable for Mouse, Bovine, Rat, and Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant human CEBPA (Asn281-Ala358).

Objetivo

CCAAT/enhancer-binding protein alpha; C/EBP alpha; CEBPA; CEBP

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

P53566, O02754, P05554, P49715

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

CCAAT/enhancer-binding protein alpha (CEBPA) is a ~37 kDa protein. Transcription factor that coordinates proliferation arrest and the differentiation of myeloid progenitors, adipocytes, hepatocytes, and cells of the lung and the placenta. Binds directly to the consensus DNA sequence 5'-T[TG]NNGNAA[TG]-3' acting as an activator on distinct target genes. During early embryogenesis, plays essential and redundant functions with CEBPB. Essential for the transition from common myeloid progenitors (CMP) to granulocyte/monocyte progenitors (GMP). Critical for the proper development of the liver and the lung.

1. Wang, GL. et al. (2004) Genes & development 18, 912-25. PMID: 15107404

2. Zhang, P. et al. (2004) Immunity 21, 853-63. PMID: 15589173

3. Zhang, Z. et al. (2022) Cell metabolism 34, 1860-1874.e4. PMID: 36228616

4. Lin, FT. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 9606-10. PMID: 8415748

5. Bégay, V. et al. (2004) Molecular and cellular biology 24, 9744-51. PMID: 15509779

6. Ohlsson, E. et al. (2014) The Journal of experimental medicine 211, 5-13. PMID: 24367003

7. Flodby, P. et al. (1996) The Journal of biological chemistry 271, 24753-60. PMID: 8798745

8. Samuelsson, L. et al. (1991) The EMBO journal 10, 3787-93. PMID: 1935900

9. Lin, FT. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 8757-61. PMID: 8090719

10. Porse, BT. et al. (2001) Cell 107, 247-58. PMID: 11672531

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-CEBPA Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

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