Anti-CEBPA Polyclonal Antibody (HW834024)

Name: Anti-CEBPA Polyclonal Antibody
Brand: abinScience
SKU: HW834024
Price: 168 USD
Availability: InStock

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100ug

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Обзор

Каталожный номер

HW834024

Описание

Anti-CEBPA Polyclonal Antibody (HW834024) is a rabbit polyclonal antibody detecting CCAAT/enhancer-binding protein alpha; C/EBP alpha; CEBPA; CEBP in ELISA, IHC, WB. Suitable for Mouse, Bovine, Rat, and Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant human CEBPA (Asn281-Ala358).

Цель

CCAAT/enhancer-binding protein alpha; C/EBP alpha; CEBPA; CEBP

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

P53566, O02754, P05554, P49715

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

CCAAT/enhancer-binding protein alpha (CEBPA) is a ~37 kDa protein. Transcription factor that coordinates proliferation arrest and the differentiation of myeloid progenitors, adipocytes, hepatocytes, and cells of the lung and the placenta. Binds directly to the consensus DNA sequence 5'-T[TG]NNGNAA[TG]-3' acting as an activator on distinct target genes. During early embryogenesis, plays essential and redundant functions with CEBPB. Essential for the transition from common myeloid progenitors (CMP) to granulocyte/monocyte progenitors (GMP). Critical for the proper development of the liver and the lung.

1. Wang, GL. et al. (2004) Genes & development 18, 912-25. PMID: 15107404

2. Zhang, P. et al. (2004) Immunity 21, 853-63. PMID: 15589173

3. Zhang, Z. et al. (2022) Cell metabolism 34, 1860-1874.e4. PMID: 36228616

4. Lin, FT. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 9606-10. PMID: 8415748

5. Bégay, V. et al. (2004) Molecular and cellular biology 24, 9744-51. PMID: 15509779

6. Ohlsson, E. et al. (2014) The Journal of experimental medicine 211, 5-13. PMID: 24367003

7. Flodby, P. et al. (1996) The Journal of biological chemistry 271, 24753-60. PMID: 8798745

8. Samuelsson, L. et al. (1991) The EMBO journal 10, 3787-93. PMID: 1935900

9. Lin, FT. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 8757-61. PMID: 8090719

10. Porse, BT. et al. (2001) Cell 107, 247-58. PMID: 11672531

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-CEBPA Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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