

| Número de catálogo | HV067014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-CFL2 Polyclonal Antibody (HV067014) is a rabbit polyclonal antibody detecting CFL2 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human CFL2 (Ala2-Leu166). | ||||||||
| Objetivo | CFL2, Cofilin-2, Cofilin, muscle isoform | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9Y281 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Cofilin-2 (CFL2) is a ~18 kDa protein. Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. Its F-actin depolymerization activity is regulated by association with CSPR3. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Required for muscle maintenance. 1. Papalouka, V. et al. (2009) Molecular and cellular biology 29, 6046-58. PMID: 19752190 | ||||||||
| Nota | For research use only. |

Western blot analysis was performed using anti-CFL2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Raji cell lysate
Lane 2: Mouse brain lysate
Lane 3: Mouse lung lysate
Lane 4: Rat brain lysate
Lane 5: Rat lung lysate
Lane 6: Rat skeletal muscle lysate



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