

| Numéro de catalogue | HB792014 | ||||||||
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| Description |
Anti-CFP Polyclonal Antibody (HB792014) is a rabbit polyclonal antibody detecting CFP in ELISA, IHC, WB. Suitable for Human and Pongo abelii.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human CFP (Gln65-Cys190). | ||||||||
| Cible | PFC, CFP, Properdin, Complement factor P | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P27918 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Properdin (CFP) is a ~51 kDa protein. A positive regulator of the alternate pathway (AP) of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b). 1. Hourcade, DE. (2006) The Journal of biological chemistry 281, 2128-32. PMID: 16301317 2. Ferreira, VP. et al. (2010) Immunobiology 215, 932-40. PMID: 20382442 3. Pedersen, DV. et al. (2017) The EMBO journal 36, 1084-1099. PMID: 28264884 4. Hourcade, DE. et al. (1998) The Journal of biological chemistry 273, 25996-6000. PMID: 9748277 5. Pedersen, DV. et al. (2019) Frontiers in immunology 10, 2007. PMID: 31507604 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-CFP polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse brain lysate
Lane 2: Rat brain lysate




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