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| カタログ番号 | HB792014 | ||||||||
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| 説明 |
Anti-CFP Polyclonal Antibody (HB792014) is a rabbit polyclonal antibody detecting CFP in ELISA, IHC, WB. Suitable for Human and Pongo abelii.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CFP (Gln65-Cys190). | ||||||||
| ターゲット | PFC, CFP, Properdin, Complement factor P | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P27918 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Properdin (CFP) is a ~51 kDa protein. A positive regulator of the alternate pathway (AP) of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b). 1. Hourcade, DE. (2006) The Journal of biological chemistry 281, 2128-32. PMID: 16301317 2. Ferreira, VP. et al. (2010) Immunobiology 215, 932-40. PMID: 20382442 3. Pedersen, DV. et al. (2017) The EMBO journal 36, 1084-1099. PMID: 28264884 4. Hourcade, DE. et al. (1998) The Journal of biological chemistry 273, 25996-6000. PMID: 9748277 5. Pedersen, DV. et al. (2019) Frontiers in immunology 10, 2007. PMID: 31507604 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-CFP polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse brain lysate
Lane 2: Rat brain lysate
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