

| Numéro de catalogue | HW473014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-CHI3L1 Polyclonal Antibody (HW473014) is a rabbit polyclonal antibody detecting CHI3L1 in ELISA, IHC, WB. Suitable for Human, Pongo abelii, and Pig.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human CHI3L1 (Asn112-Lys377). | ||||||||
| Cible | CHI3L1, GP-39, YKL-40, Chitinase-3-like protein 1, CGP-39, 39 kDa synovial protein, hCGP-39, Cartilage glycoprotein 39 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P36222 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Chitinase-3-like protein 1 (CHI3L1) is a ~42 kDa protein. Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. | ||||||||
| Note | For research use only. |



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