

| Número de catálogo | VK572024 | ||||||||
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| Descripción |
Anti-CHIKV Capsid Protein Polyclonal Antibody (VK572024) is a rabbit polyclonal antibody detecting Capsid protein in ELISA, IHC, WB. Suitable for Chikungunya virus, O'nyong-nyong virus, Middelburg virus, Ross river virus, and Sagiyama virus.
Highlights
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| Reactividad de especies | Chikungunya virus (CHIKV) | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant CHIKV Capsid Protein (Arg104-Trp261). | ||||||||
| Objetivo | C, Capsid protein, Coat protein | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Pureza | >95% as determined by SDS-PAGE. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P0DOK1, Q8JUX5, Q5WQY5, Q5XXP3, O90371, P22056, O90369, P03315, P0DJZ6, Q80S27, P08491, Q9JGK8, Q5Y388, P13890, Q8QZ72 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Envío | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||||
| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Frameshifted structural polyprotein is a ~92 kDa protein. Forms an icosahedral capsid with a T=4 symmetry composed of 240 copies of the capsid protein surrounded by a lipid membrane through which penetrate 80 spikes composed of trimers of E1-E2 heterodimers. The capsid protein binds to the viral RNA genome at a site adjacent to a ribosome binding site for viral genome translation following genome release. Possesses a protease activity that results in its autocatalytic cleavage from the nascent structural protein. Following its self-cleavage, the capsid protein transiently associates with ribosomes, and within several minutes the protein binds to viral RNA and rapidly assembles into icosahedric core particles. The resulting nucleocapsid eventually associates with the cytoplasmic domain of the spike glycoprotein E2 at the cell membrane, leading to budding and formation of mature virions. | ||||||||
| Nota | For research use only |

Lane 1: recombinant CHIKV Capsid (Catalog No: VK572022)
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