Anti-CHIKV Spike Glycoprotein E1 Recombinant Antibody (DC1.9) (VK425093)

Name: Anti-CHIKV Spike Glycoprotein E1 Recombinant Antibody (DC1.9)
Brand: abinScience
SKU: VK425093
Price: 191 USD
Availability: InStock

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Número de catálogo	VK425093
Reactividad de especies	Chikungunya virus (CHIKV)
Aplicaciones	BIF, FCM, IP
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1, kappa
ID de clon	DC1.9
Objetivo	p130, Structural polyprotein
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q8JUX5
RRID	Anti-CHIKV p130/Structural polyprotein Antibody (DC1.9) (abinScience Cat# VK425093, RRID:AB_3725335)
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo	Structural polyprotein (Spike glycoprotein E1) is a ~138 kDa protein. Forms an icosahedral capsid with a T=4 symmetry composed of 240 copies of the capsid protein surrounded by a lipid membrane through which penetrate 80 spikes composed of trimers of E1-E2 heterodimers. The capsid protein binds to the viral RNA genome at a site adjacent to a ribosome binding site for viral genome translation following genome release. Possesses a protease activity that results in its autocatalytic cleavage from the nascent structural protein. Following its self-cleavage, the capsid protein transiently associates with ribosomes, and within several minutes the protein binds to viral RNA and rapidly assembles into icosahedric core particles. The resulting nucleocapsid eventually associates with the cytoplasmic domain of the spike glycoprotein E2 at the cell membrane, leading to budding and formation of mature virions. 1. Webb, LG. et al. (2020) PLoS pathogens 16, e1008999. PMID: 33057424
Nota	For research use only.