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Anti-CHRNA2 Polyclonal Antibody (HA818014)

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Vista general
Número de catálogoHA818014
Descripción
Anti-CHRNA2 Polyclonal Antibody (HA818014) is a rabbit polyclonal antibody detecting Neuronal acetylcholine receptor subunit alpha-2; CHRNA2 in ELISA, IHC, WB. Suitable for Human, Rat, Mouse, and Chicken.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant human CHRNA2 (Glu27-Pro265).
Objetivo Neuronal acetylcholine receptor subunit alpha-2; CHRNA2
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q15822, P12389, Q91X60, P09480
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Neuronal acetylcholine receptor subunit alpha-2 (CHRNA2) is a ~59 kDa protein. Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits known to mediate synaptic transmission in the nervous system and the neuromuscular junction. Each nAchR subunit confers differential attributes to channel properties, including activation, deactivation and desensitization kinetics, pH sensitivity, cation permeability, and binding to allosteric modulators. CHRNA2 forms heteropentameric neuronal acetylcholine receptors with CHRNB2 and CHRNB4 and plays a role in nicotine dependence.

1. Millar, NS. et al. (2009) Neuropharmacology 56, 237-46. PMID: 18723036
2. Dash, B. et al. (2014) Neuropharmacology 79, 715-25. PMID: 24467848
3. Kouvatsos, N. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 9635-40. PMID: 27493220
Nota For research use only
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Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-CHRNA2 Polyclonal Antibody

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