Anti-CHRNA2 Polyclonal Antibody (HA818014)

Name: Anti-CHRNA2 Polyclonal Antibody
Brand: abinScience
SKU: HA818014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HA818014

Description

Anti-CHRNA2 Polyclonal Antibody (HA818014) is a rabbit polyclonal antibody detecting Neuronal acetylcholine receptor subunit alpha-2; CHRNA2 in ELISA, IHC, WB. Suitable for Human, Rat, Mouse, and Chicken.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant human CHRNA2 (Glu27-Pro265).

Cible

Neuronal acetylcholine receptor subunit alpha-2; CHRNA2

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

Q15822, P12389, Q91X60, P09480

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Neuronal acetylcholine receptor subunit alpha-2 (CHRNA2) is a ~59 kDa protein. Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits known to mediate synaptic transmission in the nervous system and the neuromuscular junction. Each nAchR subunit confers differential attributes to channel properties, including activation, deactivation and desensitization kinetics, pH sensitivity, cation permeability, and binding to allosteric modulators. CHRNA2 forms heteropentameric neuronal acetylcholine receptors with CHRNB2 and CHRNB4 and plays a role in nicotine dependence.

1. Millar, NS. et al. (2009) Neuropharmacology 56, 237-46. PMID: 18723036

2. Dash, B. et al. (2014) Neuropharmacology 79, 715-25. PMID: 24467848

3. Kouvatsos, N. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 9635-40. PMID: 27493220

Note

For research use only

Images

Reférences

Fiche technique

Anti-CHRNA2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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