Anti-CHRNA2 Polyclonal Antibody (HA818014)

Name: Anti-CHRNA2 Polyclonal Antibody
Brand: abinScience
SKU: HA818014
Price: 168 USD
Availability: InStock

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SDS

Обзор

Каталожный номер

HA818014

Описание

Anti-CHRNA2 Polyclonal Antibody (HA818014) is a rabbit polyclonal antibody detecting Neuronal acetylcholine receptor subunit alpha-2; CHRNA2 in ELISA, IHC, WB. Suitable for Human, Rat, Mouse, and Chicken.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant human CHRNA2 (Glu27-Pro265).

Цель

Neuronal acetylcholine receptor subunit alpha-2; CHRNA2

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

Q15822, P12389, Q91X60, P09480

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Neuronal acetylcholine receptor subunit alpha-2 (CHRNA2) is a ~59 kDa protein. Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits known to mediate synaptic transmission in the nervous system and the neuromuscular junction. Each nAchR subunit confers differential attributes to channel properties, including activation, deactivation and desensitization kinetics, pH sensitivity, cation permeability, and binding to allosteric modulators. CHRNA2 forms heteropentameric neuronal acetylcholine receptors with CHRNB2 and CHRNB4 and plays a role in nicotine dependence.

1. Millar, NS. et al. (2009) Neuropharmacology 56, 237-46. PMID: 18723036

2. Dash, B. et al. (2014) Neuropharmacology 79, 715-25. PMID: 24467848

3. Kouvatsos, N. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 9635-40. PMID: 27493220

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-CHRNA2 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

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