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| カタログ番号 | HV486014 | ||||||||
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| 説明 |
Anti-CILK1 Polyclonal Antibody (HV486014) is a rabbit polyclonal antibody detecting CILK1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CILK1 (Met1-Gln277). | ||||||||
| ターゲット | Ciliogenesis associated kinase 1, Serine/threonine-protein kinase ICK, MAK-related kinase, ICK, KIAA0936, hICK, Laryngeal cancer kinase 2, CILK1, MRK, LCK2, Intestinal cell kinase | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9UPZ9 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Serine/threonine-protein kinase ICK (CILK1) is a ~71 kDa protein. Required for ciliogenesis. Phosphorylates KIF3A. Involved in the control of ciliary length. Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips. May play a key role in the development of multiple organ systems and particularly in cardiac development. 1. Chaya, T. et al. (2014) The EMBO journal 33, 1227-42. PMID: 24797473 2. Moon, H. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 8541-6. PMID: 24853502 | ||||||||
| 注意事項 | For research use only. |
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