

| Número de catálogo | HY210014 | ||||||
|---|---|---|---|---|---|---|---|
| Descripción |
Anti-CKB Polyclonal Antibody (HY210014) is a rabbit polyclonal antibody detecting CKB in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Bovine.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||
| Aplicaciones | ELISA, IHC, WB | ||||||
| Especie huésped | Rabbit | ||||||
| Clonalidad | Polyclonal | ||||||
| Isotipo | IgG | ||||||
| Inmunógeno | E. coli - derived recombinant Human CKB (Pro2-Lys381). | ||||||
| Objetivo | Creatine phosphokinase B-type, Creatine kinase B-type, CKBB, CPK-B, Brain creatine kinase, Creatine kinase B chain, B-CK, CKB | ||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||
| Purificación | Purified by antigen affinity column. | ||||||
| Número de acceso | P12277 | ||||||
| Forma | Liquid | ||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Reconstitución | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||
| Envío | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||
| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| Fondo | Creatine kinase B-type (CKB) is a ~42 kDa protein. Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (Probable). Acts as a key regulator of adaptive thermogenesis as part of the futile creatine cycle: localizes to the mitochondria of thermogenic fat cells and acts by mediating phosphorylation of creatine to initiate a futile cycle of creatine phosphorylation and dephosphorylation. During the futile creatine cycle, creatine and N-phosphocreatine are in a futile cycle, which dissipates the high energy charge of N-phosphocreatine as heat without performing any mechanical or chemical work. 1. Lin, L. et al. (1994) Biochimica et biophysica acta 1206, 97-104. PMID: 8186255 | ||||||
| Nota | For research use only. |
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