

| Número de catálogo | HW507014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-CLCN7 Polyclonal Antibody (HW507014) is a rabbit polyclonal antibody detecting CLCN7 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
|
||||||||
| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human CLCN7 (Phe597-Thr805). | ||||||||
| Objetivo | Chloride channel 7 alpha subunit, CLCN7, ClC-7, Chloride channel protein 7, H(+)/Cl(-) exchange transporter 7 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P51798 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
||||||||
| Información de uso del producto |
| ||||||||
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | H(+)/Cl(-) exchange transporter 7 (CLCN7) is a ~88 kDa protein. Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen and may be involved in maintaining lysosomal pH. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters. 1. Graves, AR. et al. (2008) Nature 453, 788-92. PMID: 18449189 2. Leisle, L. et al. (2011) The EMBO journal 30, 2140-52. PMID: 21527911 3. Nicoli, ER. et al. (2019) American journal of human genetics 104, 1127-1138. PMID: 31155284 | ||||||||
| Nota | For research use only. |
Contáctenos para cotizaciones personalizadas, solicitudes en masa y cualquier otro problema.
Correo: [email protected]
Acceso rápido
Contáctenos
+86-027-65523339
Edificio C, No. 666, Calle Shendunsi, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский