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| カタログ番号 | HB593014 | ||||||||
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| 説明 |
Anti-CLIC3 Polyclonal Antibody (HB593014) is a rabbit polyclonal antibody detecting Chloride intracellular channel protein 3; CLIC3 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human CLIC3 (Asp45-Arg236). | ||||||||
| ターゲット | Chloride intracellular channel protein 3; CLIC3 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O95833, Q9D7P7 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Chloride intracellular channel protein 3 (CLIC3) is a ~26 kDa protein. In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Reduced in a glutathione-dependent way and secreted into the extracellular matrix where it activates TGM2 and promotes blood vessel growth during tissue remodeling as occurs in tumorigenesis. Can reduce specific cysteines in TGM2 and regulate cofactor binding. Can insert into membranes and form outwardly rectifying chloride ion channels. May participate in cellular growth control. 1. Hernandez-Fernaud, JR. et al. (2017) Nature communications 8, 14206. PMID: 28198360 2. Alghalayini, A. et al. (2023) Biomolecules 13. PMID: 37759794 | ||||||||
| 注意事項 | For research use only |
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