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| カタログ番号 | HV578024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CNDP2 (Met1-Asp475). | ||||||||
| ターゲット | Peptidase A, PEPA, CNDP2, Carnosine dipeptidase II, CN2, Epididymis secretory protein Li 13, Glutamate carboxypeptidase-like protein 1, CNDP dipeptidase 2, HEL-S-13, Cytosolic non-specific dipeptidase, CPGL | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q96KP4 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Cytosolic non-specific dipeptidase (CNDP2) is a ~52 kDa protein. Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides. Mediates threonyl dipeptide catabolism in a tissue-specific way. Has high dipeptidase activity toward cysteinylglycine, an intermediate metabolite in glutathione metabolism. Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis. Plays a role in the regulation of cell cycle arrest and apoptosis. 1. Teufel, M. et al. (2003) The Journal of biological chemistry 278, 6521-31. PMID: 12473676 2. Kaur, H. et al. (2009) The Journal of biological chemistry 284, 14493-502. PMID: 19346245 3. Jansen, RS. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 6601-6. PMID: 25964343 4. Zhang, P. et al. (2006) Clinical cancer research : an official journal of the American Association for Cancer Research 12, 6617-25. PMID: 17121880 5. Zhang, Z. et al. (2014) Molecular medicine (Cambridge, Mass.) 20, 17-28. PMID: 24395568 | ||||||||
| 注意事項 | For research use only. |
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