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| カタログ番号 | HV038014 | ||||||||
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| 説明 |
Anti-CNOT6 Polyclonal Antibody (HV038014) is a rabbit polyclonal antibody detecting CNOT6 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Xenopus laevis.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CNOT6 (Leu153-Arg557). | ||||||||
| ターゲット | KIAA1194, CCR4, CNOT6, CCR4a, CCR4 carbon catabolite repression 4-like, Cytoplasmic deadenylase, Carbon catabolite repressor protein 4 homolog, CCR4-NOT transcription complex subunit 6 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9ULM6 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | CCR4-NOT transcription complex subunit 6 (CNOT6) is a ~63 kDa protein. Poly(A) nuclease with 3'-5' RNase activity. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in mRNA decay mediated by the major-protein-coding determinant of instability (mCRD) of the FOS gene in the cytoplasm. In the presence of ZNF335, enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA. | ||||||||
| 注意事項 | For research use only. |
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