Anti-COQ6 Polyclonal Antibody (HV325014)

Name: Anti-COQ6 Polyclonal Antibody
Brand: abinScience
SKU: HV325014
Price: 168 USD
Availability: InStock

データシート製品共有情報コピー

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HV325014

説明

Anti-COQ6 Polyclonal Antibody (HV325014) is a rabbit polyclonal antibody detecting COQ6 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human COQ6 (Met1-Lys468).

ターゲット

Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial, COQ6, Coenzyme Q10 monooxygenase 6

精製

Purified by antigen affinity column.

アクセッション番号

Q9Y2Z9

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial is a ~50 kDa protein. FAD-dependent monooxygenase required for two non-consecutive steps during ubiquinone biosynthesis. Required for the C5-ring hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 4-hydroxy-3-(all-trans-decaprenyl)benzoic acid to 3,4-dihydroxy-5-(all-trans-decaprenyl)benzoic acid. Also acts downstream of COQ4, for the C1-hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 2-methoxy-6-(all-trans-decaprenyl)phenol to 2-methoxy-6-(all-trans-decaprenyl)benzene-1,4-diol. The electrons required for the hydroxylation reaction are funneled indirectly to COQ6 from NADPH via a ferredoxin/ferredoxin reductase system composed of FDX2 and FDXR.

1. Ozeir, M. et al. (2015) The Journal of biological chemistry 290, 24140-51. PMID: 26260787

2. Nicoll, CR. et al. (2024) Nature catalysis 7, 148-160. PMID: 38425362

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-COQ6 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-COQ6 Polyclonal Antibody (HV325014)

概要

イメージ

参考文献

データシート

SDS

クイックアクセス

お問い合わせ