

| Numéro de catalogue | HW510014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-CSNK1A1 Polyclonal Antibody (HW510014) is a rabbit polyclonal antibody detecting CSNK1A1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Chicken.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human CSNK1A1 (Lys130-Phe337). | ||||||||
| Cible | CK1, Casein kinase I isoform alpha, CSNK1A1, CKI-alpha | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P48729 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Casein kinase I isoform alpha (CSNK1A1) is a ~38 kDa protein. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. 1. Liu, C. et al. (2002) Cell 108, 837-47. PMID: 11955436 2. Brockman, JL. et al. (1992) Proceedings of the National Academy of Sciences of the United States of America 89, 9454-8. PMID: 1409656 3. Gonzales, ML. et al. (2008) The Journal of biological chemistry 283, 12665-73. PMID: 18305108 4. Kuga, T. et al. (2013) Journal of cell science 126, 4721-31. PMID: 23902688 5. Gao, D. et al. (2011) Molecular cell 44, 290-303. PMID: 22017875 6. Duan, S. et al. (2011) Molecular cell 44, 317-24. PMID: 22017877 | ||||||||
| Note | For research use only. |
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