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Anti-CSNK1A1 Polyclonal Antibody (HW510014)

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Aperçu
Numéro de catalogueHW510014
Description
Anti-CSNK1A1 Polyclonal Antibody (HW510014) is a rabbit polyclonal antibody detecting CSNK1A1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Chicken.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human CSNK1A1 (Lys130-Phe337).
Cible CK1, Casein kinase I isoform alpha, CSNK1A1, CKI-alpha
Purification Purified by antigen affinity column.
Numéro d'accès P48729
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Casein kinase I isoform alpha (CSNK1A1) is a ~38 kDa protein. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2.

1. Liu, C. et al. (2002) Cell 108, 837-47. PMID: 11955436
2. Brockman, JL. et al. (1992) Proceedings of the National Academy of Sciences of the United States of America 89, 9454-8. PMID: 1409656
3. Gonzales, ML. et al. (2008) The Journal of biological chemistry 283, 12665-73. PMID: 18305108
4. Kuga, T. et al. (2013) Journal of cell science 126, 4721-31. PMID: 23902688
5. Gao, D. et al. (2011) Molecular cell 44, 290-303. PMID: 22017875
6. Duan, S. et al. (2011) Molecular cell 44, 317-24. PMID: 22017877
Note For research use only.
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Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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