

| Número de catálogo | HA661014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-CSRP3 Polyclonal Antibody (HA661014) is a rabbit polyclonal antibody detecting cardiac; Muscle LIM protein; CSRP3; CLP; MLP in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Rat.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant human CSRP3 (Met1-Glu194). | ||||||||
| Objetivo | Cysteine and glycine-rich protein 3; Cardiac LIM protein; Cysteine-rich protein 3; CRP3; LIM domain protein, cardiac; Muscle LIM protein; CSRP3; CLP; MLP | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P50461, P50462, Q4U0T9, P50463 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Cysteine and glycine-rich protein 3 (CSRP3) is a ~20 kDa protein. Positive regulator of myogenesis. Acts as a cofactor for myogenic bHLH transcription factors such as MYOD1, and probably MYOG and MYF6. Enhances the DNA-binding activity of the MYOD1:TCF3 isoform E47 complex and may promote formation of a functional MYOD1:TCF3 isoform E47:MEF2A complex involved in myogenesis. Plays a crucial and specific role in the organization of cytosolic structures in cardiomyocytes. Could play a role in mechanical stretch sensing. 1. Papalouka, V. et al. (2009) Molecular and cellular biology 29, 6046-58. PMID: 19752190 2. Hoffmann, C. et al. (2014) Molecular and cellular biology 34, 3053-65. PMID: 24934443 3. Lange, S. et al. (2016) Nature communications 7, 12120. PMID: 27353086 | ||||||||
| Nota | For research use only |

Western blot analysis was performed using anti-CSRP3 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse heart lysate
Lane 2: Rat heart lysate
Lane 3: Rat skeletal muscle lysate
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