

| Número de catálogo | HW624014 | ||||||||
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| Descripción |
Anti-CTNNA1 Polyclonal Antibody (HW624014) is a rabbit polyclonal antibody detecting CTNNA1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human CTNNA1 (Gly666-Ser846). | ||||||||
| Objetivo | Renal carcinoma antigen NY-REN-13, Catenin alpha-1, CTNNA1, Alpha E-catenin, Cadherin-associated protein | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P35221 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Catenin alpha-1 (CTNNA1) is a ~100 kDa protein. Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. | ||||||||
| Nota | For research use only. |
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