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| カタログ番号 | HW624014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-CTNNA1 Polyclonal Antibody (HW624014) is a rabbit polyclonal antibody detecting CTNNA1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CTNNA1 (Gly666-Ser846). | ||||||||
| ターゲット | Renal carcinoma antigen NY-REN-13, Catenin alpha-1, CTNNA1, Alpha E-catenin, Cadherin-associated protein | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P35221 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Catenin alpha-1 (CTNNA1) is a ~100 kDa protein. Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. | ||||||||
| 注意事項 | For research use only. |
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