Anti-CTSL Polyclonal Antibody (HY099014)

Name: Anti-CTSL Polyclonal Antibody
Brand: abinScience
SKU: HY099014
Price: 168 USD
Availability: InStock

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50ug
100ug

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Vista general

Número de catálogo

HY099014

Descripción

Anti-CTSL Polyclonal Antibody (HY099014) is a rabbit polyclonal antibody detecting CTSL in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human CTSL (Ala114-Thr288).

Objetivo

CTSL1, MEP, Procathepsin L, Major excreted protein, Cathepsin L1, CTSL

Purificación

Purified by antigen affinity column.

Número de acceso

P07711

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Procathepsin L (CTSL) is a ~37 kDa protein. Thiol protease important for the overall degradation of proteins in lysosomes (Probable). Plays a critical for normal cellular functions such as general protein turnover, antigen processing and bone remodeling. Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. In neuroendocrine chromaffin cells secretory vesicles, catalyzes the prohormone proenkephalin processing to the active enkephalin peptide neurotransmitter. In thymus, regulates CD4(+) T cell positive selection by generating the major histocompatibility complex class II (MHCII) bound peptide ligands presented by cortical thymic epithelial cells.

1. Felbor, U. et al. (2000) The EMBO journal 19, 1187-94. PMID: 10716919

Nota

For research use only.

Imágenes

Referencias

Datasheet