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| カタログ番号 | HY099014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-CTSL Polyclonal Antibody (HY099014) is a rabbit polyclonal antibody detecting CTSL in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human CTSL (Ala114-Thr288). | ||||||||
| ターゲット | CTSL1, MEP, Procathepsin L, Major excreted protein, Cathepsin L1, CTSL | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P07711 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Procathepsin L (CTSL) is a ~37 kDa protein. Thiol protease important for the overall degradation of proteins in lysosomes (Probable). Plays a critical for normal cellular functions such as general protein turnover, antigen processing and bone remodeling. Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. In neuroendocrine chromaffin cells secretory vesicles, catalyzes the prohormone proenkephalin processing to the active enkephalin peptide neurotransmitter. In thymus, regulates CD4(+) T cell positive selection by generating the major histocompatibility complex class II (MHCII) bound peptide ligands presented by cortical thymic epithelial cells. 1. Felbor, U. et al. (2000) The EMBO journal 19, 1187-94. PMID: 10716919 | ||||||||
| 注意事項 | For research use only. |
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