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| カタログ番号 | HA544014 | ||||||||
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| 説明 |
Anti-DAXX Polyclonal Antibody (HA544014) is a rabbit polyclonal antibody in WB, IHC, ELISA. Suitable for Human, Mus musculus, and Rattus norvegicus.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | WB, IHC, ELISA | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 純度 | >90% as determined by SDS-PAGE. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9UER7 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 別名 | Death domain-associated protein 6, Daxx, hDaxx, ETS1-associated protein 1, EAP1, Fas death domain-associated protein, DAXX | ||||||||
| 背景 | Death domain-associated protein 6 (DAXX) is a ~81 kDa protein. Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Inhibits transcriptional activation of PAX3 and ETS1 through direct protein-protein interactions. 1. Boellmann, F. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 4100-5. PMID: 15016915 | ||||||||
| 注意事項 | For research use only. |
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