Anti-DCAF15 Polyclonal Antibody (HB522014)

Name: Anti-DCAF15 Polyclonal Antibody
Brand: abinScience
SKU: HB522014
Price: 168 USD
Availability: InStock

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50ug
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SDS

Обзор

Каталожный номер

HB522014

Описание

Anti-DCAF15 Polyclonal Antibody (HB522014) is a rabbit polyclonal antibody detecting DDB1- and CUL4-associated factor 15; DCAF15; C19orf72 in ELISA, IHC, WB. Suitable for Human, Bovine, Mouse, and Frog.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant human DCAF15 (Tyr386-Val564).

Цель

DDB1- and CUL4-associated factor 15; DCAF15; C19orf72

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

Q66K64, Q3SZD5, Q6PFH3, A2BDA5

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

DDB1- and CUL4-associated factor 15 (DCAF15) is a ~66 kDa protein. Substrate-recognition component of the DCX(DCAF15) complex, a cullin-4-RING E3 ubiquitin-protein ligase complex that mediates ubiquitination and degradation of target proteins. The DCX(DCAF15) complex acts as a regulator of the natural killer (NK) cells effector functions, possibly by mediating ubiquitination and degradation of cohesin subunits SMC1A and SMC3. May play a role in the activation of antigen-presenting cells (APC) and their interaction with NK cells.

1. Jin, J. et al. (2006) Molecular cell 23, 709-21. PMID: 16949367

2. Pech, MF. et al. (2019) eLife 8. PMID: 31452512

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-DCAF15 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

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