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Anti-DEFA3 Polyclonal Antibody (HX987014)

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Aperçu
Numéro de catalogueHX987014
Description
Anti-DEFA3 Polyclonal Antibody (HX987014) is a rabbit polyclonal antibody detecting DEFA3 in ELISA, IHC, WB. Suitable for Human, Macaca mulatta, Pan troglodytes, and Papio hamadryas.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human DEFA3 (Pro21-Cys94).
Cible HP3, Neutrophil defensin 3, HNP-3, HNP-2, DEF3, HP-3, Defensin, alpha 3, DEFA3, HP-2, HP2
Purification Purified by antigen affinity column.
Numéro d'accès P59666
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Neutrophil defensin 3 (DEFA3) is a ~10 kDa protein. Effector molecule of the innate immune system that acts via antibiotic-like properties against a broad array of infectious agents including bacteria, fungi, and viruses. Possesses the ability to neutralize bacterial toxins such as B.anthracis lethal factor, Clostridium difficile cytotoxin B as well as leukocidin produced by Staphylococcus aureus. Also blocks herpes simplex virus infection by interacting with envelope glycoprotein B and thus preventing its binding to heparan sulfate, the receptor for attachment.

1. Ericksen, B. et al. (2005) Antimicrobial agents and chemotherapy 49, 269-75. PMID: 15616305
2. Kim, C. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 4830-5. PMID: 15772169
3. Hazrati, E. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 177, 8658-66. PMID: 17142766
4. Giesemann, T. et al. (2008) Gastroenterology 134, 2049-58. PMID: 18435932
5. Cardot-Martin, E. et al. (2015) Letters in applied microbiology 61, 158-64. PMID: 25963798
Note For research use only.
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Reférences
Fiche technique
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-DEFA3 Polyclonal Antibody

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